Danish teenager Holger Rune has eliminated 2021 French Open runner-up Stefanos Tsitsipas to reach his first major quarterfinal in his Roland Garros debut.

The 40th-ranked Rune beat fourth-seeded Tsitsipas 7-5, 3-6, 6-3, 6-4 at Court Philippe Chatrier on Monday. Tsitsipas is the first member of the top eight seeds to leave the men`s bracket.