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High-fat diets can impair immune, intestinal and brain health: Study
Updated On: 06 January, 2024 08:14 AM IST | New York | IANS
Word on the street is that plant-based diets are better for you, and in many cases that`s true. However, a diet high in fat, even from a plant, is one case where it`s just not true, said Frances Sladek, a cell biology professor at University of California - Riverside who conducted the research
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High-fat diets affect genes linked not only to obesity, colon cancer and irritable bowels, but also to the immune system, brain function, according to a study in mouse models. Researchers at the University of California - Riverside fed mice three different diets over the course of 24 weeks where at least 40 per cent of the calories came from fat. Then, they looked not only at the microbiome, but also at genetic changes in all four parts of the intestines.
One group of mice ate a diet based on saturated fat from coconut oil, another got a monounsaturated, modified soybean oil, and a third got an unmodified soybean oil high in polyunsaturated fat. Compared to a low-fat control diet, all three groups experienced concerning changes in gene expression, the process that turns genetic information into a functional product, such as a protein.
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