Updated On: 03 June, 2023 04:42 PM IST | Berlin | ANI
Research has found that unless you happen to have PDE3A gene mutation which causes severe hypertension that also shields the kidneys from harm, the organs will be affected

Image for representational purpose only. Photo Courtesy: istock
A new research published in `Kidney International` by a team of scientists led by Enno Klussmann of the Max Delbruck Centre and the DZHK, has found that unless you happen to have PDE3A gene mutation, high blood pressure eventually damages the kidneys. It means that the mutation that causes severe hypertension also shields the kidneys from harm.
"This mutation causes extremely high blood pressure, but the kidneys still work normally even after years of having the condition," said Dr Enno Klussmann, head of the Anchored Signalling Lab in Berlin. He and his team at the Max Delbruck Center and at the German Center for Cardiovascular Research (DZHK), have now published their results in "Kidney International."
Getting to the heart of the matter
Last year, researchers discovered that the gene mutation responsible for causing extremely high blood pressure and short fingers (hypertension and brachydactyly, or HTNB) also protects the heart from hypertension-induced damage.