Family history may raise risk of some lung cancers: Study

While smoking tobacco is one of the major reasons behind lung cancer a new study suggests genes may also be a risk factorThe study published in journal The Lancet showed evidence for a family history of lung cancer in individuals who do not smokeThe study included 12011 people from Taiwan where lung cancers occur predominantly in neversmokers and of whom nearly 60 per cent have stage IV disease at diagnosisldquoIn individuals who do not smoke our findings suggest that a family history of lung cancer among firstdegree relatives significantly increases the risk of lung cancer as well as the rate of invasive lung cancer with increasing agerdquo said researchers including from the National Taiwan University in TaipeiThe team aimed to assess the efficacy of lowdose CT LDCT screening among neversmokers who had other risk factors for lung cancerBetween 2015 and 2019 they examined 12011 people of which 6009 had a family history of lung cancerThe prevalence of invasive lung cancer was higher among participants with a family history of lung cancer 161 2middot7 per cent of 6009 participants than in those without 96 1middot6 per cent of 6002 participantsIn participants with a family history of lung cancer the higher the number of firstdegree relatives affected the higher the risk of lung cancer participants whose mother or sibling had lung cancer were also at an increased riskIn participants with a family history of lung cancer the detection rate of invasive lung cancer increased significantly with age whereas the detection rate of adenocarcinoma in situ remained stable Adenocarcinomas are cancers that start in glandular tissues that make mucus or fluid such as the lung breast prostate or colonIn multivariable analysis female sex a family history of lung cancer and age older than 60 years were associated with an increased risk of lung cancer and invasive lung cancer passive smoke exposure cumulative exposure to cooking cooking without ventilation and a previous history of chronic lung diseases were not associated with lung cancer even after stratification by family history of lung cancerldquoFurther research on risk factors for lung cancer in this population is needed particularly for those without a family history of lung cancerrdquo the researchers saidThis story has been sourced from a third party syndicated feed agencies Midday accepts no responsibility or liability for its dependability trustworthiness reliability and data of the text Midday managementmiddaycom reserves the sole right to alter delete or remove without notice the content in its absolute discretion for any reason whatsoever