Childhood allergies like skin, lungs begin in the gut Study

Major childhood allergies eczema asthma food allergy and hay fever may likely begin in the community of bacteria living in our gut according to a new studyMany factors can shape the infant gut microbiota including diet how we are born where we live and our exposure to antibioticsFor example antibiotics may wipe out sensitive bacteria while breastfeeding tends to replenish and provide necessary food for bacteria in the infant gutWere seeing more and more children and families seeking help at the emergency department due to allergies said Dr Stuart Turvey Professor in the department of paediatrics at the University of British ColumbiaHundreds of millions of children worldwide suffer from allergies and its important to understand why this is happening and how it can be prevented added Turvey an investigator at BC Childrens Hospital Research InstituteThe research published in the journal Nature Communications examined how these types of influences affected the balance of gut microbiota and the development of these allergies that affect more than a third of people worldwideFor the study researchers examined clinical assessments from 1115 children who were tracked from birth to age fiveRoughly half of the children 523 had no evidence of allergies at any time while more than half 592 were diagnosed with one or more allergic disorders by an expert physicianThe researchers evaluated the childrens microbiomes from stool samples collected at clinical visits at three months and one year of ageThe stool samples revealed a bacterial signature that was associated with the children developing any of the four allergies by five years of ageThe bacterial signature is a hallmark of dysbiosis or an imbalanced gut microbiota that likely resulted in a compromised intestinal lining and an elevated inflammatory response within the gutTypically our bodies tolerate the millions of bacteria living in our guts because they do so many good things for our health Some of the ways we tolerate them are by keeping a strong barrier between them and our immune cells and by limiting inflammatory signals that would call those immune cells into action said Courtney Hoskinson a doctoral candidate at UBCWe found a common breakdown in these mechanisms in babies prior to the development of allergies she addedThe findings could lead to methods of predicting whether a child will develop allergies and ways to prevent them from developing at allDeveloping therapies that change these interactions during infancy may therefore prevent the development of all sorts of allergic diseases in childhood which often last a lifetime Turvey saidThis story has been sourced from a third party syndicated feed agencies Midday accepts no responsibility or liability for its dependability trustworthiness reliability and data of the text Midday managementmiddaycom reserves the sole right to alter delete or remove without notice the content in its absolute discretion for any reason whatsoever